3β-hsd activity assay (RAMSEY MEDICAL INC)
90
Structured Review
RAMSEY MEDICAL INC
3β-hsd activity assay
3β Hsd Activity Assay, supplied by RAMSEY MEDICAL INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/3%CE%B2-hsd+activity+assay/3%CE%B2+hsd+activity+assay/pm11262455-104-21-9
Average 90 stars, based on 1 article reviews
3β Hsd Activity Assay, supplied by RAMSEY MEDICAL INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/3%CE%B2-hsd+activity+assay/3%CE%B2+hsd+activity+assay/pm11262455-104-21-9
Average 90 stars, based on 1 article reviews
3β-hsd activity assay - by Bioz Stars,
2026-10
90/100 stars
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other:Article Title: Troglitazone is a competitive inhibitor of 3beta-hydroxysteroid dehydrogenase enzyme in the ovary. Article Snippet: Troglitazone improves insulin resistance in peripheral tissues and represents a member of a new drug class for the treatment of type 2 diabetes mellitus.1, 2 Troglitazone and other thiazolidinediones act primarily on adipose and muscle tissue, where they increase insulin sensitivity at the postreceptor level.. This improvement in insulin resistance is the basis for their use in diabetes treatment.1 Thiazolidinediones are believed to act primarily by modulating the expression of genes that regulate glucose homeostasis by binding to and activating the nuclear receptor peroxisome proliferator–activated receptor γ (PPARγ).3 In addition to treating type 2 diabetes mellitus, thiazolidinediones produce beneficial effects in a variety of diseases such as dyslipidosis, endothelial dysfunction, and platelet aggregation.4 In the reproductive system, thiazolidinediones have been studied in the treatment of polycystic ovary syndrome (PCOS).. Because thiazolidinediones decrease hyperinsulinemia, it was hypothesized that they may be useful in decreasing elevated insulin concentrations associated with the syndrome and therefore in reducing the enhanced steroidogenesis and associated hyperandrogenism and menstrual dysfunction. |